Application library
B.7C·Biology·DNA & Protein Synthesis

Mutations in the real world

Explain how substitutions, insertions, and deletions in DNA can change proteins and traits.

Transfer evidence, not just familiar practice

Correctly solve different fresh variations at least 24 hours after your first correct transfer response. Reviewing the same challenge again does not count as fresh retention evidence.

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Career · Genetic engineering and clinical genomics

Gene editing review board

A review board evaluates two edits: one inserts a nucleotide immediately after a bacterial start codon, and another creates a premature stop codon in a human disease allele.

Why this TEKS matters

The location and type of a DNA change determine whether reading frames shift or translation ends early, which can strongly alter protein function.

Challenge 1

Assess an early insertion

Explain why one inserted nucleotide near the start can affect more of the protein than a later substitution.

Challenge 2

Classify a premature stop

Identify the mutation outcome created when an amino-acid codon becomes a stop codon.

Everyday life · Personal genomics and science media

Understanding DNA test results

A DNA report describes one substitution that leaves the amino acid unchanged and another deletion that removes exactly one internal codon from an engineered enzyme.

Why this TEKS matters

Not every mutation changes a protein in the same way: silent substitutions preserve an amino acid, while in-frame deletions remove one without shifting later codons.

Challenge 3

Interpret a silent substitution

Predict the likely outcome when GCU and GCC both specify alanine.

Challenge 4

Interpret an in-frame deletion

Determine the direct effect of removing all three nucleotides of one internal codon.